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Letters To The Editor

By Various Authors, 1965
To the Editor:
The family of the late Aldous Hux­ley has authorized me to prepare an edition of his letters for publica­tion by Harper & Row of New York and by Chatto & Windus, Ltd., London. I should be most grateful if any owners of letters from Al­dous Huxley would be kind enough to send them (or copies) to me for this purpose. Original letters would of course be treated with the great­est care, and after being copied would be returned immediately.
Sincerely yours,
Grover Smith
Associate Professor of English
Duke University
Durham, North Carolina

To the Editor:
Have any chemists looked for psychedelic substances in locoweed? The name is apparently taken from the Spanish "loco," meaning "mad" because of the behavior it induces in animals who have eaten the plants.

The plant is a member of the legume family and found chiefly in the Western United States. Several species have been identified as poi­sonous to horses, cattle, sheep and goats. The U. S. Department of Ag­riculture has listed the plant in Farmers' Bulletin No. 2106, August 1964 titled "16 Plants Poisonous to Livestock in the Western States" but the toxic chemical is not iden­tified, and I have not been able to find any reference to chemical work with the plant.

The effect it has on animals is quite interesting. They appar­ently lose their sense of direction and walk with an irregular gait; they are nervous, weak and with­draw from other animals. They may react violently when disturbed. "Locoed" horses seldom recover completely and are considered use­less for saddle or work animals so are usually destroyed by their own­er. Most animals suffer a weight loss and are therefore of no value for beef. Losses caused by abortion are frequently high when large amounts of the weed are ingested (could this be another ergot com­pound?).

Animals ordinarily will not eat the weed unless feed is scarce, but once they start eating it, they seem to acquire a taste for it termed the "loco habit" and will seek out the plants even when other forage is available. Symptoms of poisoning will usually appear within two to three weeks of continuous grazing on the plants.

I could not find any reference to the effect of locoweed on people. The USDA claims that locoweeds are poisonous during all stages of growth, and may be dangerous throughout the year. All parts of the plant are toxic, even after being stored in dry form for two to three years.

The following list is from the USDA Bulletin and is included for anyone who cares to search out more information about the plants. The list includes the 'Common Name'for each plant; followed by the 'Botanical Name'; and finally the location it is commonly found.
  1. White loco; Oxytropis Lambertii; Montana and North Dakota, south to Arizona, New Mexi­co, and Texas.
  2. Purple, or wooly loco; Astragalus mollissimus; South Dakota to western Texas to New Mexi­co.
  3. Blue loco; A. lentiginosus; Eastern Washing­ton, Idaho, Utah, Col­orado, Ne­vada, and California
  4. Bigbend loco; A. earlei; western Texas and southern New Mexico.
  5. Western lolo; A wootoni; eastern Arizona, southern New Mexi­co, and southwestern Texas.
Sincerely, Marjorie B. King Fair Oaks, Calif.


On the American desert are horses which eat the locoweed and some are driven mad by it; their vision is affected, they take enor­mous leaps to cross a tuft of grass or tumble blindly into rivers. The horses which have become thus ad­dicted are shunned by the others and will never rejoin the herd. So it is with human beings: those who are conscious of another world, the world of the spirit, acquire an outlook which distorts the values of ordinary life; they are con­sumed by the weed of non-attach­ment.

Curiosity is their one excess and therefore they are recognized not by what they do, but by what they refrain from doing, like those Araphants or disciples of Buddha who were pledged to the "Nine In-capabilities." Thus they do not take life, they do not compete, they do not boast, they do not join groups of more than six, they do not condemn others; they are "abandoners of revels, mute, contemplative" who wait to be tele­phoned to, who neither speak in public, nor keep up with their friends, nor take revenge on their enemies.

Self-knowledge has taught them to abandon hate and blame and envy in their lives, and they look sadder than they are. They seldom make positive assertions be­cause they see, outlined against any statement, as a painter sees a com­plementary color, the image of its opposite. Most psychological ques­tionnaires are designed to search out these moonlings and to secure their non-employment. They di­vine each other by a warm indiffer­ence for they know that they are not intended to forgather, but, like stumps of phosphorus in the world's wood, each to give forth his mis­leading radiance.

From: The Unquiet Grave; A Word Cycle; by Palinurus (Cyril Connolly); Viking Press, N. Y., 1945., P. 32-33.

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